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YM-I-26

Product Specifications

CAS Number

2585015-90-1

Target

Interleukin|||NOD-like Receptor (NLR)

Related Pathways

Immunology/Inflammation

Bioactivity

YM-I-26 is a selective inhibitor of the NLRP3 inflammasome. This compound enhances the phagocytic activity of ?-amyloid in murine microglial BV2 cells and reduces the production of IL-1? and IL-10. YM-I-26 is useful for research into inflammation-related immunomodulatory activities.

Smiles

O=C(N(CC1=CC(Cl)=CC=C1OCCC)CCC2=CC=C(C=C2)S(=O)(=O)N3CCOCC3)CC4=CSC=C4

Molecular Formula

C28H33ClN2O5S2

Molecular Weight

577.16

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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