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FKB04

Product Specifications

Target

Others|||Telomerase

Related Pathways

Others|||DNA Damage/DNA Repair

Bioactivity

FKB04 is a telomeric repeat binding factor 2 (TRF2) inhibitor that exerts its antitumor activity by disrupting the telomere maintenance mechanisms in hepatocellular carcinoma cells. This leads to T-loop defects, inducing telomere shortening and cellular senescence. Additionally, FKB04 inhibits tumor growth in a human liver cancer xenograft mouse model (by implanting Huh-7 cells in BALB/c mice) . This compound is utilized in research focused on liver cancer.

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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