10-Methoxy-canthin-6-one
Product Specifications
CAS Number
86293-40-5
Target
P38 MAPK
Related Pathways
MAPK
Bioactivity
10-Methoxy-canthin-6-one (Mtx-C) acts as a DNA damage inducer that embeds into DNA, promoting cell cycle arrest at the G2/M phase. This process triggers myeloid differentiation in acute myeloid leukemia cells (AML) and leukemia stem cells (LSC) . Differentiation in AML and LSC cells is characterized by increased expression of myeloperoxidase, CD15, CD11b, and CD14, along with the activation of p38 MAPK. 10-Methoxy-canthin-6-one is utilized in the study of leukemia.
Smiles
O=C1C=CC2=NC=CC=3C4=CC(OC)=CC=C4N1C23
Molecular Formula
C15H10N2O2
Molecular Weight
250.25
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Product Datasheet
https://www.targetmol.com/attachment/DataSheet/250676858469744643/T200611
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS1150480-01 0.02 mg (E-Coli)
Recombinant Bacillus subtilis N5-carboxyaminoimidazole ribonucleotide synthase (purK)
Ask
View Details 
MBS1150480-02 0.02 mg (Yeast)
Recombinant Bacillus subtilis N5-carboxyaminoimidazole ribonucleotide synthase (purK)
Ask
View Details 
MBS1150480-03 0.1 mg (E-Coli)
Recombinant Bacillus subtilis N5-carboxyaminoimidazole ribonucleotide synthase (purK)
Ask
View Details MBS1150480-04 0.1 mg (Yeast)
Recombinant Bacillus subtilis N5-carboxyaminoimidazole ribonucleotide synthase (purK)
Ask
View Details MBS1150480-05 0.02 mg (Baculovirus)
Recombinant Bacillus subtilis N5-carboxyaminoimidazole ribonucleotide synthase (purK)
Ask
View Details 
MBS1150480-06 0.02 mg (Mammalian-Cell)
Recombinant Bacillus subtilis N5-carboxyaminoimidazole ribonucleotide synthase (purK)
Ask
View Details