MPGES1-IN-5
Product Specifications
CAS Number
2253745-70-7
Target
Others, PGE Synthase
Related Pathways
Immunology/Inflammation, Others
Bioactivity
MPGES1-IN-5 (compound 18) is a multi-substituted pyrimidine compound that acts as a submicromolar inhibitor of PGE2 production. It primarily exerts its anti-inflammatory effects by inhibiting mPGES-1 and demonstrates significant inhibitory activity in vivo against acute inflammation models.
Smiles
N=1C(=NC(C=2C=CC(OCC=3C=CC=CC3)=CC2)=C(C1C=4C=CC=CC4)CCCC)N
Molecular Formula
C27H27N3O
Molecular Weight
409.52
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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