GK241
Product Specifications
CAS Number
1899930-93-8
Target
Others
Related Pathways
Others
Bioactivity
GK241 (compound 31a-c), a 2-oxoamide-based compound, exhibits inhibitory activity against group IIA secretory phospholipase A2 (GIIA sPLA2) in humans and mice, with IC50 values of 143 nM and 68 nM, respectively. The mechanism of inhibition has been explored through molecular dynamics simulations.
Smiles
[C@H](NC(C(CCCCCCCCCCCCCC)=O)=O)([C@H](C)C)C(O)=O
Molecular Formula
C21H39NO4
Molecular Weight
369.54
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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