What is the catalog number for NOD1/2-IN-1?

The catalog number for NOD1/2-IN-1 is T200582.

What sizes are available for NOD1/2-IN-1?

NOD1/2-IN-1 is available in the following size(s): 10 mg, 50 mg.

How many pack sizes does NOD1/2-IN-1 come in?

NOD1/2-IN-1 is available in 2 different pack sizes.

Is NOD1/2-IN-1 in stock?

NOD1/2-IN-1 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures NOD1/2-IN-1?

NOD1/2-IN-1 is manufactured by Molfinity.

What is the estimated delivery time for NOD1/2-IN-1?

Estimated delivery time for NOD1/2-IN-1 is approximately 10 business day(s), depending on your location.

NOD1/2-IN-1

Product Specifications

Target

NOD-like Receptor (NLR), RIP kinase

Related Pathways

Immunology/Inflammation, NF-κB, Apoptosis

Bioactivity

NOD1/2-IN-1 (Compound 18) is a potent RIPK2 inhibitor, demonstrating an IC50 value of 1.4 nM in the ADP-Glo assay. It blocks the production of pro-inflammatory cytokines by inhibiting the NOD1/NOD2 pathway (IC50 values are 18 nM and 170 nM for NOD1 and NOD2, respectively), thereby reducing inflammatory responses. This compound is utilized in research related to colitis.