What is the catalog number for HCAIX-IN-23?

The catalog number for HCAIX-IN-23 is T200575.

What sizes are available for HCAIX-IN-23?

HCAIX-IN-23 is available in the following size(s): 10 mg, 50 mg.

How many pack sizes does HCAIX-IN-23 come in?

HCAIX-IN-23 is available in 2 different pack sizes.

Is HCAIX-IN-23 in stock?

HCAIX-IN-23 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures HCAIX-IN-23?

HCAIX-IN-23 is manufactured by Molfinity.

What is the estimated delivery time for HCAIX-IN-23?

Estimated delivery time for HCAIX-IN-23 is approximately 10 business day(s), depending on your location.

HCAIX-IN-23

Product Specifications

Target

Carbonic Anhydrase, Apoptosis, Ferroptosis, Reactive Oxygen Species, Caspase, Mitochondrial Metabolism

Related Pathways

Immunology/Inflammation, NF-κB, Metabolism, Apoptosis, Proteases/Proteasome

Bioactivity

HCAIX-IN-23 (Compound 27) is a human carbonic anhydrase (hCA) inhibitor with Ki values of 10.4 nM for hCA IX and 8.5 nM for hCA XII. It not only inhibits hCA activity but also releases NO, exerting dual anti-tumor effects. By reducing the expression of hCA IX and iron regulatory proteins, hCAIX-IN-23 regulates mitochondrial caspase activity and the ferroptosis pathway, thereby inducing apoptosis. This compound is utilized in research focused on renal cancer.