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MGluR2 modulator 5

Product Specifications

CAS Number

1639898-35-3

Target

GluR

Related Pathways

Neuroscience

Bioactivity

MGluR2 modulator5 (Compound 11) is a selective negative allosteric modulator with oral activity, exhibiting an IC50 of 8.9 nM. Pharmacokinetic studies in rats have demonstrated its effective penetration through the blood-brain barrier. This compound is utilized in research related to cognitive and neurological functions in mood disorders, contributing to the field of neurological diseases.

Smiles

O=C1C2=C(C=NN2[C@@H](C)CN1C3=CC=C(C(F)(F)F)C=C3)C=4C=C(C)N=CC4

Molecular Formula

C20H17F3N4O

Molecular Weight

386.37

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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