MGluR2 modulator 5
Product Specifications
CAS Number
1639898-35-3
Target
GluR
Related Pathways
Neuroscience
Bioactivity
MGluR2 modulator5 (Compound 11) is a selective negative allosteric modulator with oral activity, exhibiting an IC50 of 8.9 nM. Pharmacokinetic studies in rats have demonstrated its effective penetration through the blood-brain barrier. This compound is utilized in research related to cognitive and neurological functions in mood disorders, contributing to the field of neurological diseases.
Smiles
O=C1C2=C(C=NN2[C@@H](C)CN1C3=CC=C(C(F)(F)F)C=C3)C=4C=C(C)N=CC4
Molecular Formula
C20H17F3N4O
Molecular Weight
386.37
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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