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MPGES1-IN-4

Product Specifications

CAS Number

2253745-78-5

Target

Others, PGE Synthase

Related Pathways

Others, Immunology/Inflammation

Bioactivity

MPGES1-IN-4 (compound 32) is a multi-substituted pyrimidine compound acting as a submicromolar inhibitor of PGE2 production. It primarily exerts its anti-inflammatory effects by inhibiting mPGES-1 and significantly suppresses acute inflammation models in vivo.

Smiles

FC=1C(F)=C(C=CC1OCC=2C=CC=CC2)C=3N=C(N=C(C=4C=CC=CC4)C3CCCC)N

Molecular Formula

C27H25F2N3O

Molecular Weight

445.5

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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