MPGES1-IN-4
Product Specifications
CAS Number
2253745-78-5
Target
Others|||PGE Synthase
Related Pathways
Others|||Immunology/Inflammation
Bioactivity
MPGES1-IN-4 (compound 32) is a multi-substituted pyrimidine compound acting as a submicromolar inhibitor of PGE2 production. It primarily exerts its anti-inflammatory effects by inhibiting mPGES-1 and significantly suppresses acute inflammation models in vivo.
Smiles
FC=1C(F)=C(C=CC1OCC=2C=CC=CC2)C=3N=C(N=C(C=4C=CC=CC4)C3CCCC)N
Molecular Formula
C27H25F2N3O
Molecular Weight
445.5
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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