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PF470

Product Specifications

CAS Number

1539296-45-1

Target

Others|||GluR

Related Pathways

Neuroscience|||Others

Bioactivity

PF470 (PF-06297470) is a negative allosteric modulator of the metabotropic glutamate receptor 5 (mGluR5), which demonstrated significant therapeutic effects in Parkinson's disease models. However, its clinical development was halted due to potential issues identified in toxicological studies.

Smiles

N=1C=CC(=C(C1)C2=NN(C=3N=C(OCC4=NC=CC=C4)C=NC23)C)C

Molecular Formula

C18H16N6O

Molecular Weight

332.36

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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