PF470
Product Specifications
CAS Number
1539296-45-1
Target
Others|||GluR
Related Pathways
Neuroscience|||Others
Bioactivity
PF470 (PF-06297470) is a negative allosteric modulator of the metabotropic glutamate receptor 5 (mGluR5), which demonstrated significant therapeutic effects in Parkinson's disease models. However, its clinical development was halted due to potential issues identified in toxicological studies.
Smiles
N=1C=CC(=C(C1)C2=NN(C=3N=C(OCC4=NC=CC=C4)C=NC23)C)C
Molecular Formula
C18H16N6O
Molecular Weight
332.36
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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