MerTK/Axl-IN-1
Product Specifications
CAS Number
3036009-40-9
Target
TAM Receptor
Related Pathways
Tyrosine Kinase/Adaptors
Bioactivity
MerTK/Axl-IN-1 (Compound A-910) is a potent and selective dual inhibitor of MerTK/Axl, exhibiting IC50 values of 4.2 nM and 8.8 nM in Ba/F3 cells, and 0.2 nM and 0.9 nM in HTRF cells, respectively. It effectively inhibits pMerTK in vivo and possesses a long half-life and high oral bioavailability.
Smiles
C([C@@H](CO)O)N1CCN([C@@H]2C=3C(=CC(=CC3)C4=CC=C(CO[C@@H]5[C@@H](NC(=O)C=6C=C(C=NC6N)C7=C(F)N=CC=C7)CCC5)C=C4)CCC2)CC1
Molecular Formula
C40H47FN6O4
Molecular Weight
694.84
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS6378104-01 0.1 mL
FANCC (Fanconi Anemia Group C Protein, Protein FACC, FAC, FACC) (MaxLight 550)
Ask
View Details 
MBS6378104-02 5x 0.1 mL
FANCC (Fanconi Anemia Group C Protein, Protein FACC, FAC, FACC) (MaxLight 550)
Ask
View Details 031179-ML650 100 µL
PAX6 (PAX6, AN2, Paired box protein Pax-6, Aniridia type II protein, Oculorhombin) (MaxLight 650) discontinued
Ask
View Details 
