What is the catalog number for CDK/HDAC-IN-4?

The catalog number for CDK/HDAC-IN-4 is T200504.

What sizes are available for CDK/HDAC-IN-4?

CDK/HDAC-IN-4 is available in the following size(s): 10 mg, 50 mg.

How many pack sizes does CDK/HDAC-IN-4 come in?

CDK/HDAC-IN-4 is available in 2 different pack sizes.

Is CDK/HDAC-IN-4 in stock?

CDK/HDAC-IN-4 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CDK/HDAC-IN-4?

CDK/HDAC-IN-4 is manufactured by Molfinity.

What is the estimated delivery time for CDK/HDAC-IN-4?

Estimated delivery time for CDK/HDAC-IN-4 is approximately 10 business day(s), depending on your location.

CDK/HDAC-IN-4

Product Specifications

Target

Apoptosis, HDAC, CDK

Related Pathways

Cell Cycle/Checkpoint, DNA Damage/DNA Repair, Chromatin/Epigenetic, Apoptosis

Bioactivity

CDK/HDAC-IN-4 is a highly selective dual inhibitor of cyclin-dependent kinase (CDK) and histone deacetylase (HDAC), with IC50 values of 88.4 nM and 168.9 nM, respectively. This compound exhibits antiproliferative effects in both hematologic and solid tumor cells. Additionally, CDK/HDAC-IN-4 induces apoptosis and S-phase cell cycle arrest in MV-4-11 cells. It has also demonstrated significant antitumor efficacy in an MV-4-11 xenograft model.