STAT3-IN-35
Product Specifications
CAS Number
2849535-96-0
Target
STAT
Related Pathways
Stem Cells, JAK/STAT signaling
Bioactivity
STAT3-IN-35 is a STAT3 inhibitor that binds to the SH2 domain. This compound inhibits the phosphorylation of STAT3 and exhibits antiproliferative activity in triple-negative breast cancer (TNBC) cell lines. Additionally, STAT3-IN-35 has demonstrated toxicity and potent antitumor activity in TNBC xenograft models.
Smiles
O=C1C2=C(C=3C(C1=O)=CC=CC3)OC4=C2CCN([C@@H](CC(C)C)CO)C4
Molecular Formula
C21H23NO4
Molecular Weight
353.41
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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