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PARP1-IN-31

Product Specifications

CAS Number

684234-60-4

Target

Apoptosis|||PARP|||Caspase

Related Pathways

Apoptosis|||Chromatin/Epigenetic|||Proteases/Proteasome|||DNA Damage/DNA Repair

Purity

0.9899

Bioactivity

PARP1-IN-31 (compound 11f) is a PARP1 inhibitor with an IC?? of 97 nM. It induces apoptosis and inhibits proliferation in lung cancer cell lines (e.g., A549), while upregulating caspase-3 and caspase-9, making it suitable for lung adenocarcinoma research.

Smiles

O=C(NC1=CC=C(F)C=C1)CN2N=C(C=3C=CC(Cl)=CC3)C=4C=CC=CC4C2=O

Molecular Formula

C22H15ClFN3O2

Molecular Weight

407.83

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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