PARP1-IN-31
Product Specifications
CAS Number
684234-60-4
Target
Apoptosis, PARP, Caspase
Related Pathways
Apoptosis, Chromatin/Epigenetic, Proteases/Proteasome, DNA Damage/DNA Repair
Purity
0.9899
Bioactivity
PARP1-IN-31 (compound 11f) is a PARP1 inhibitor with an IC50 of 97 nM. It induces apoptosis and inhibits proliferation in lung cancer cell lines (e.g., A549), while upregulating caspase-3 and caspase-9, making it suitable for lung adenocarcinoma research.
Smiles
O=C(NC1=CC=C(F)C=C1)CN2N=C(C=3C=CC(Cl)=CC3)C=4C=CC=CC4C2=O
Molecular Formula
C22H15ClFN3O2
Molecular Weight
407.83
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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