Ferroptosis inducer-6

Ferroptosisinducer 6 (6d) is an inducer of ferroptosis (ferroptosis) that exhibits potent potential for Type I/II photodynamic therapy by inducing ROS production, oxidative stress, and mitochondrial damage. Additionally, it demonstrates antitumor activity.

F[P-](F)(F)(F)(F)F.CC(C=C1C2=[N]3C=CC(CN4CCN(CC4)CC5=CC=CC=C5)=C2)=CC=[N]1[Ru+2]637([N]8=CC=C(C)C=C8C9=[N]7C=CC(CN%10CCN(CC%10)CC%11=CC=CC=C%11)=C9)[N]%12=CC=C(C)C=C%12C%13=[N]6C=CC(CN(CC%14)CCN%14CC%15=CC=CC=C%15)=C%13.F[P-](F)(F)(F)(F)F