And1 degrader 1
Product Specifications
CAS Number
3029132-46-2
Target
Others, DNA/RNA Synthesis
Related Pathways
Others, DNA Damage/DNA Repair, Cell Cycle/Checkpoint
Bioactivity
And1 degrader 1 (Compound A15) is a degrader of acidic nucleoplasmic DNA-binding protein 1 (And1) that notably induces degradation of And1 in NSCLC cells. When combined with Olaparib (1 μM), And1 degrader 1 at a concentration of 5 μM effectively inhibits proliferation in A549 and H460 cells. This compound is applicable in cancer research studies.
Smiles
N(CC1=CC(/C=C/C2=CC(Cl)=C(Cl)C=C2)=CC=C1O)C3=CC=C(C=C3)N4CCN(C)CC4
Molecular Formula
C26H27Cl2N3O
Molecular Weight
468.42
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
RDR-C6-Hu-48Tests 48 Tests
Human Complement Component 6 (C6) ELISA Kit
Sign In for Pricing
View Details 
MBS1266319-01 0.01 mg Plasmid + 0.2 mL Glycerol-Stock
INPP5K cDNA Clone
Sign In for Pricing
View Details MBS1266319-02 5x 0.01 mg Plasmid + 5x 0.2 mL Glycerol-Stock
INPP5K cDNA Clone
Sign In for Pricing
View Details 
abx493066-01 96 Tests
Human Transglutaminase 1, Keratinocyte (TGM1) CLIA Kit
Sign In for Pricing
View Details abx493066-02 5x 96 Tests
Human Transglutaminase 1, Keratinocyte (TGM1) CLIA Kit
Sign In for Pricing
View Details abx493066-03 10x 96 Tests
Human Transglutaminase 1, Keratinocyte (TGM1) CLIA Kit
Sign In for Pricing
View Details