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FLT3/HDAC-IN-1

Product Specifications

Target

Apoptosis, FLT, HDAC

Related Pathways

Tyrosine Kinase/Adaptors, Apoptosis, Chromatin/Epigenetic, DNA Damage/DNA Repair, Angiogenesis

Bioactivity

FLT3/HDAC-IN-1 is a dual inhibitor targeting FLT3 and HDAC, with IC50 values of 30.4 nM for FLT3 and 52.4, 14.7 nM for HDAC1/3, respectively. It induces apoptosis in MV-4-11 cells and exhibits antiproliferative effects against BaF3 cells transformed by FLT3 mutations. FLT3/HDAC-IN-1 is useful for research on refractory solid tumors and hematological malignancies.

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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