BRD8518
Product Specifications
CAS Number
1565828-01-4
Target
LDLR
Related Pathways
Metabolism
Bioactivity
BRD8518, a PCSK9 inhibitor (EC50=0.23 μM), effectively lowers lipid levels by upregulating LDLR expression and enhancing the uptake of LDL. This compound is utilized in cardiovascular disease research.
Smiles
O=C1C=2C(OC[C@]3([C@@](N1C)(CC[C@@H](CC(NC4CC=5C(C4)=CC=CC5)=O)O3)[H])[H])=CC=C(NC(=O)C6=CC=C(C(F)(F)F)C=C6)C2
Molecular Formula
C33H32F3N3O5
Molecular Weight
607.62
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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