BRD8518

Product Specifications

CAS Number

1565828-01-4

Target

LDLR

Related Pathways

Metabolism

Bioactivity

BRD8518, a PCSK9 inhibitor (EC50=0.23 ?M), effectively lowers lipid levels by upregulating LDLR expression and enhancing the uptake of LDL. This compound is utilized in cardiovascular disease research.

Smiles

O=C1C=2C(OC[C@]3([C@@](N1C)(CC[C@@H](CC(NC4CC=5C(C4)=CC=CC5)=O)O3)[H])[H])=CC=C(NC(=O)C6=CC=C(C(F)(F)F)C=C6)C2

Molecular Formula

C33H32F3N3O5

Molecular Weight

607.62

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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