STAT3-IN-34
Product Specifications
Target
STAT
Related Pathways
Stem Cells, JAK/STAT signaling
Bioactivity
STAT3-IN-34 (Compound 15E) acts as a STAT3 inhibitor, blocking both the nuclear translocation and the transcriptional regulator activity of STAT3. It effectively inhibits HaCaT cell proliferation with an IC50 value of 0.008 μM. Additionally, STAT3-IN-34 reduces IL-17A expression and mitigates Imiquimod-induced psoriasis in mouse models.
Molecular Formula
C19H16N2O4S
Molecular Weight
368.41
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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