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C-Met/HDAC-IN-4

Product Specifications

Target

Apoptosis, c-Met/HGFR, HDAC

Related Pathways

Apoptosis, Chromatin/Epigenetic, Tyrosine Kinase/Adaptors, DNA Damage/DNA Repair

Bioactivity

C-Met/HDAC-IN-4, a dual inhibitor of c-Met/HDAC, exhibits an IC 50 value of 28.92 nM for c-Met. This compound effectively induces G 0 /G 1 phase cell cycle arrest and apoptosis in MDA-MB-231 breast cancer cells. Additionally, c-Met/HDAC-IN-4 suppresses both the proliferation and invasion of breast cancer cell lines.

Molecular Formula

C37H36N8O

Molecular Weight

608.73

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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