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STAT3/HDAC-IN-2

Product Specifications

Target

STAT, HDAC

Related Pathways

Chromatin/Epigenetic, JAK/STAT signaling, DNA Damage/DNA Repair, Stem Cells

Bioactivity

STAT3/HDAC-IN-2 (compound 18), a dual inhibitor of STAT3 and HDAC, promotes autophagy and apoptosis. This compound features an amphiphilic hydroxamic acid hybrid structure, derived from the natural product isopropanol lactone (IAL), and functions as a nanoscale anticancer agent. It has the ability to self-assemble into nanoparticles in aqueous environments, leading to enhanced tumor tissue accumulation, increased cellular uptake, and improved anticancer efficacy compared to its free state.

Molecular Formula

C28H32N2O7

Molecular Weight

508.56

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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