Top1/2-IN-1
Product Specifications
Target
Topoisomerase
Related Pathways
DNA Damage/DNA Repair
Bioactivity
Compound 23, known as Top1/2-IN-1, is a dual inhibitor of Top1/2 that can be administered orally and exhibits antiproliferative effects. It induces apoptosis and cell cycle arrest in cancer cells by damaging DNA and elevating reactive oxygen species levels. Additionally, Top1/2-IN-1 demonstrates antitumor activity in vivo within xenograft models.
Molecular Formula
C21H21N3O2
Molecular Weight
347.41
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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