SD-7300
Product Specifications
CAS Number
748120-89-0
Target
MMP
Related Pathways
Proteases/Proteasome
Bioactivity
SD-7300 (SC-81490) functions as an orally active inhibitor targeting MMP-2, MMP-9, and MMP-13, exhibiting potent inhibition with K_i values of 0.03, 0.01, and 0.03 nM, respectively. By inhibiting these metalloproteinases, SD-7300 effectively reduces extracellular matrix degradation by tumor cells, thereby curbing their invasion and metastasis. Additionally, this compound acts as a dose-dependent inhibitor of mouse corneal angiogenesis and prevents interleukin-1-induced degradation of bovine cartilage. SD-7300 is applicable in the study of breast cancer.
Smiles
O=C(NO)C1(CCN(CCOC)CC1)S(=O)(=O)N2CCC(OC3=CC=C(OC(F)(F)F)C=C3)CC2
Molecular Formula
C21H30F3N3O7S
Molecular Weight
525.54
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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