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LBG20304

Product Specifications

Target

IGluR

Related Pathways

Membrane transporter/Ion channel|||Neuroscience

Bioactivity

LBG20304 (compound 2s) serves as a ligand for the homologous GluK5 receptor, demonstrating an IC50 of 432 nM and exhibiting over 40-fold selectivity against the GluK1-3 isoforms. At concentrations below 10 ?M, LBG20304 shows neither agonistic nor antagonistic effects on heterologous GluK2/5 receptors. However, at concentrations above 10 ?M, it displays minimal agonist activity in neuronal slices (rat) .

Molecular Formula

C19H18N4O5

Molecular Weight

382.37

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

Curated Selection

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