INI-4001
Product Specifications
CAS Number
2549050-07-7
Target
TLR
Related Pathways
Immunology/Inflammation
Bioactivity
INI-4001, a TLR7/8 agonist, exhibits EC50 values of 1.89 μM and 4.86 μM for TLR7 and TLR8, respectively. This compound induces signal transduction and SEAP production through TLR7 and TLR8. Furthermore, INI-4001 stimulates the production of high-affinity, fentanyl-specific antibodies, effectively preventing fentanyl from crossing the human blood-brain barrier. It serves as an effective adjuvant in anti-fentanyl vaccines for individuals with opioid use disorder (OUD) .
Smiles
C(N1C=2C(NC1=O)=C(N)N=C(O[C@H](CCC)C)N2)C3CCN(CCOP(OCCOCCOCCOC[C@H](OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O)(=O)O)CC3
Molecular Formula
C59H109N6O13P
Molecular Weight
1141.5
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
GTR15148924 1 Vial
Lentiviral mouse Ikzf3 shRNA (UAS) - Lentiviral mouse Ikzf3 shRNA (UAS, iRFP) plasmid
Sign In for Pricing
View Details 
orb2841107 100 µL
Phospho-Tie2 (Ser1119) Rabbit pAb, PerCP-Cy7 conjugated
Sign In for Pricing
View Details 