Sabialimon P
Product Specifications
CAS Number
2267333-96-8
Target
COX, NF-κB, Interleukin, NO Synthase, TNF
Related Pathways
Neuroscience, Apoptosis, Immunology/Inflammation, NF-κB
Bioactivity
Sabialimon P (compound 16), with an IC50 of 18.12 μM, functions as a NO release inhibitor and exhibits anti-inflammatory properties. It effectively diminishes the secretion of TNF-α, iNOS, IL-6, and NF-κB, and suppresses the expression of COX-2 and NF-κB/p65 in LPS-induced RAW264.7 cells.
Smiles
C(OC)(=O)[C@]12[C@](C=3[C@@](C)(CC1)[C@@]4(C)[C@](CC3)([C@]5(C)[C@@](CC4)(C(C)(C)[C@@H](O)C[C@@H]5O)[H])[H])(CC(C)(C)CC2)[H]
Molecular Formula
C31H50O4
Molecular Weight
486.73
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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