Sabialimon P
Product Specifications
CAS Number
2267333-96-8
Target
COX|||NF-?B|||Interleukin|||NO Synthase|||TNF
Related Pathways
Neuroscience|||Apoptosis|||Immunology/Inflammation|||NF-?B
Bioactivity
Sabialimon P (compound 16), with an IC50 of 18.12 ?M, functions as a NO release inhibitor and exhibits anti-inflammatory properties. It effectively diminishes the secretion of TNF-?, iNOS, IL-6, and NF-?B, and suppresses the expression of COX-2 and NF-?B/p65 in LPS-induced RAW264.7 cells.
Smiles
C(OC)(=O)[C@]12[C@](C=3[C@@](C)(CC1)[C@@]4(C)[C@](CC3)([C@]5(C)[C@@](CC4)(C(C)(C)[C@@H](O)C[C@@H]5O)[H])[H])(CC(C)(C)CC2)[H]
Molecular Formula
C31H50O4
Molecular Weight
486.73
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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