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YL-5092

Product Specifications

CAS Number

3056857-07-6

Target

Apoptosis, Cell Cycle Arrest

Related Pathways

Apoptosis, Cell Cycle/Checkpoint

Bioactivity

YL-5092 is a YTHDC1 inhibitor (IC50=7.4 nM, KD=29.6 nM) that suppresses cancer cell proliferation, induces G0/G1 phase arrest and apoptosis, and can be used in studies of acute myeloid leukemia (AML) .

Smiles

O=C(NC=1C=CC(=CC1)C=2SC=NC2)C3=CC(=CN3)C(=O)C=4C=CC=CC4C(F)(F)F

Molecular Formula

C22H14F3N3O2S

Molecular Weight

441.43

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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