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ERK-MYD88 interaction inhibitor 1

Product Specifications

CAS Number

2215927-89-0

Target

Apoptosis

Related Pathways

Apoptosis

Bioactivity

ERK-MYD88 Interaction Inhibitor 1, an agent that disrupts the interaction between ERK and MYD88, has demonstrated the ability to trigger an HRI-mediated integrated stress response (ISR) that specifically promotes immunogenic cell apoptosis (apoptosis) in cancer cells. Additionally, in models using Lewis lung cancer mice, this compound has been shown to stimulate anti-tumor T cell responses, thereby exhibiting significant anti-tumor activity.

Smiles

O=C(NC1=CN=C(OC)C=C1)C2=CC=C3N=C(NC3=C2)C=4C=CC(=CC4)N(C)C

Molecular Formula

C22H21N5O2

Molecular Weight

387.43

Shipping Conditions

Cool pack

Storage Temperature

-20°C

Available Sizes

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