ERK-MYD88 interaction inhibitor 1
Product Specifications
CAS Number
2215927-89-0
Target
Apoptosis
Related Pathways
Apoptosis
Bioactivity
ERK-MYD88 Interaction Inhibitor 1, an agent that disrupts the interaction between ERK and MYD88, has demonstrated the ability to trigger an HRI-mediated integrated stress response (ISR) that specifically promotes immunogenic cell apoptosis (apoptosis) in cancer cells. Additionally, in models using Lewis lung cancer mice, this compound has been shown to stimulate anti-tumor T cell responses, thereby exhibiting significant anti-tumor activity.
Smiles
O=C(NC1=CN=C(OC)C=C1)C2=CC=C3N=C(NC3=C2)C=4C=CC(=CC4)N(C)C
Molecular Formula
C22H21N5O2
Molecular Weight
387.43
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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