KRASG12C IN-14
Product Specifications
Target
Ras
Related Pathways
GPCR/G Protein, MAPK
Bioactivity
KRASG12C IN-14 (compound 15), a potent inhibitor specifically designed for the KRAS G12C mutation, exhibits impressive efficacy in impeding CYPA-dependent KRAS-BRAF interaction and ERK phosphorylation in NCI-H358 cells, both with an IC 50 of 0.002 μM.
Molecular Formula
C51H65F4N9O9S2
Molecular Weight
1088.24
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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