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KRASG12C IN-14

Product Specifications

Target

Ras

Related Pathways

GPCR/G Protein, MAPK

Bioactivity

KRASG12C IN-14 (compound 15), a potent inhibitor specifically designed for the KRAS G12C mutation, exhibits impressive efficacy in impeding CYPA-dependent KRAS-BRAF interaction and ERK phosphorylation in NCI-H358 cells, both with an IC 50 of 0.002 μM.

Molecular Formula

C51H65F4N9O9S2

Molecular Weight

1088.24

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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