FO-4-15
Product Specifications
CAS Number
1030759-58-0
Target
GluR|||CaMK|||Microtubule Associated
Related Pathways
Neuroscience|||Cytoskeletal Signaling
Bioactivity
FO-4-15 is an activator of mGluR1/CaMKII?. It exhibits protective effects against H2O2 in human neuroblastoma (SH-SY5Y) cells. In mice with Alzheimer's disease, FO-4-15 enhances cognitive function by activating the mGluR1/CaMKII? pathway, reducing A? accumulation, Tau hyperphosphorylation, and synaptic damage.
Smiles
O=S(=O)(C1=CC=C(C=C1)C)N2CCN(CC3=NC(=NO3)C=4OC=CC4)CC2
Molecular Formula
C18H20N4O4S
Molecular Weight
388.44
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
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