PF-07899895

3033846-10-2

SIK

PI3K/Akt/mTOR signaling

PF-07899895 (compound 34) is a potent SIK (salt-induced kinase) inhibitor with IC50 values of 1.2/0.9/1.8 nM for SIK1/SIK2/SIK3.

N#CC1=CC=CC2=NC=C(C=3C=C(OCC4(N)CCCCC4)C(C#N)=C(SC)C3)N12

C23H23N5OS

417.53

Cool pack

-20°C