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XMU-MP-9

Product Specifications

CAS Number

2251130-41-1

Target

Ras

Related Pathways

MAPK, GPCR/G Protein

Bioactivity

XMU-MP-9, a bifunctional compound, targets the C2 domain of Nedd4-1 and the allosteric site of K-Ras. It enhances the interaction and induces conformational changes within the Nedd4-1/K-Ras complex. Furthermore, XMU-MP-9 facilitates the ubiquitination and degradation of various K-Ras mutants and inhibits the proliferation of cells with these mutants. This compound is useful in cancer research.

Smiles

O=C(NCC=1C(F)=CC=CC1Cl)C2=CSC(=C2)C3=NNC=4C=CC=CC34

Molecular Formula

C19H13ClFN3OS

Molecular Weight

385.84

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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