XMU-MP-9
Product Specifications
CAS Number
2251130-41-1
Target
Ras
Related Pathways
MAPK|||GPCR/G Protein
Bioactivity
XMU-MP-9, a bifunctional compound, targets the C2 domain of Nedd4-1 and the allosteric site of K-Ras. It enhances the interaction and induces conformational changes within the Nedd4-1/K-Ras complex. Furthermore, XMU-MP-9 facilitates the ubiquitination and degradation of various K-Ras mutants and inhibits the proliferation of cells with these mutants. This compound is useful in cancer research.
Smiles
O=C(NCC=1C(F)=CC=CC1Cl)C2=CSC(=C2)C3=NNC=4C=CC=CC34
Molecular Formula
C19H13ClFN3OS
Molecular Weight
385.84
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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