PROTAC Cbl-b-IN-1
Product Specifications
CAS Number
3035210-39-7
Target
Others, PROTACs
Related Pathways
Others, PROTAC
Bioactivity
PROTAC Cbl-b-IN-1 is a PROTAC that targets Cbl-b. It is composed of the PROTAC targeting protein ligand Cbl-b-IN-21, PROTAC Linker Cbz-Pip-2C-Pip-C-Pip, and the E3 ubiquitin ligase ligand (3S) Lenalidomide-5-Br. The conjugate of the E3 ubiquitin ligase ligand and Linker is (3S) Lenalidomide-5-Pip-C-Pip-2C-Pip.
Smiles
C(O)=O.C(F)(F)(F)C=1C=2N(C(=O)N(C2)C3=CC([C@@H](C4CCC4)C=5N(C)C=NN5)=CC=C3)C=C(CN6CCN(CCN7CCC(CN8CCN(CC8)C=9C=C%10C(=CC9)C(=O)N(C%10)[C@@H]%11C(=O)NC(=O)CC%11)CC7)CC6)C1
Molecular Formula
C53H65F3N12O6
Molecular Weight
1023.16
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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View Details PC109515-04 250 mg
8-chloro-3- ((2-chloro-5-fluoropyrimidin-4-yl) thio) -6- (trifluoromethyl) -[1,2,4]triazolo[4,3-a]pyridine
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View Details PC109515-05 500 mg
8-chloro-3- ((2-chloro-5-fluoropyrimidin-4-yl) thio) -6- (trifluoromethyl) -[1,2,4]triazolo[4,3-a]pyridine
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View Details PC109515-06 1 g
8-chloro-3- ((2-chloro-5-fluoropyrimidin-4-yl) thio) -6- (trifluoromethyl) -[1,2,4]triazolo[4,3-a]pyridine
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