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GBM CSCs-IN-1

Product Specifications

Target

Apoptosis

Related Pathways

Apoptosis

Bioactivity

GBM CSCs-IN-1 (Compound (−) -20), a rocaglate derivative, potently inhibits glioblastoma stem cells (GBM CSCs) and exhibits an EC50 of 45 nM by targeting the RNA helicase DDX3. Additionally, it induces apoptosis in these cells.

Molecular Formula

C28H29BrN2O8S

Molecular Weight

633.51

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

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