TMU 35435
Product Specifications
CAS Number
2231800-32-9
Target
Autophagy, HDAC
Related Pathways
Autophagy, DNA Damage/DNA Repair, Chromatin/Epigenetic
Bioactivity
TMU 35435 is an inhibitor of histone deacetylases (HDAC) . It enhances radiosensitivity by inducing the accumulation of misfolded proteins and autophagy (autophagy) in TNBC, and inhibits the NHEJ pathway through ubiquitination of the catalytic subunit of DNA-dependent protein kinase (DNA-PKcs) .
Smiles
O=C(NCCCCCCC(=O)NO)C1=CC=CC=2C=C3C=CC=C(C3=NC21)C
Molecular Formula
C22H25N3O3
Molecular Weight
379.45
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
Frequently Asked Questions
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