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TMU 35435

Product Specifications

CAS Number

2231800-32-9

Target

Autophagy, HDAC

Related Pathways

Autophagy, DNA Damage/DNA Repair, Chromatin/Epigenetic

Bioactivity

TMU 35435 is an inhibitor of histone deacetylases (HDAC) . It enhances radiosensitivity by inducing the accumulation of misfolded proteins and autophagy (autophagy) in TNBC, and inhibits the NHEJ pathway through ubiquitination of the catalytic subunit of DNA-dependent protein kinase (DNA-PKcs) .

Smiles

O=C(NCCCCCCC(=O)NO)C1=CC=CC=2C=C3C=CC=C(C3=NC21)C

Molecular Formula

C22H25N3O3

Molecular Weight

379.45

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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