What is the catalog number for KL-50?

The catalog number for KL-50 is T200136.

What sizes are available for KL-50?

KL-50 is available in the following size(s): 25 mg, 50 mg, 100 mg.

How many pack sizes does KL-50 come in?

KL-50 is available in 3 different pack sizes.

KL-50 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures KL-50?

KL-50 is manufactured by Molfinity.

What is the estimated delivery time for KL-50?

Estimated delivery time for KL-50 is approximately 10 business day(s), depending on your location.

KL-50

Product Specifications

CAS Number

1161826-19-2

Target

DNA/RNA Synthesis, Others

Related Pathways

DNA Damage/DNA Repair, Cell Cycle/Checkpoint, Others

Bioactivity

KL-50, a selective toxin, effectively targets tumors deficient in the DNA repair protein O6-methylguanine-DNA-methyltransferase (MGMT), which corrects O6-alkylguanine lesions. This compound induces both DNA damage response pathways and cell cycle arrest in MGMT-deficient cells, regardless of mismatch repair (MMR) status. KL-50 shows promise in the study of brain tumors lacking MGMT.