What is the catalog number for HDAC-IN-76?

The catalog number for HDAC-IN-76 is T200090.

What sizes are available for HDAC-IN-76?

HDAC-IN-76 is available in the following size(s): 10 mg, 50 mg.

How many pack sizes does HDAC-IN-76 come in?

HDAC-IN-76 is available in 2 different pack sizes.

Is HDAC-IN-76 in stock?

HDAC-IN-76 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures HDAC-IN-76?

HDAC-IN-76 is manufactured by Molfinity.

What is the estimated delivery time for HDAC-IN-76?

Estimated delivery time for HDAC-IN-76 is approximately 10 business day(s), depending on your location.

HDAC-IN-76

Product Specifications

Target

HDAC

Related Pathways

DNA Damage/DNA Repair, Chromatin/Epigenetic

Bioactivity

HDAC-IN-76 (compound 6i), a histone deacetylase (HDAC) inhibitor, demonstrates robust antimalarial activity, particularly against the asexual blood stages of Plasmodium. The compound exhibits potent efficacy with IC 50 values of 30 nM and 98 nM against Pf3D7 (chloroquine drug-susceptible strain) and PfDd2 (chloroquine drug-resistant strain), respectively. Moreover, HDAC-IN-76 shows selective inhibition towards parasites, displaying IC 50 values of 7 nM and 9 nM against human HDAC1 and HDAC6, respectively, and effectively inhibits PfHDAC1.