KT D606
Product Specifications
CAS Number
1429063-06-8
Target
PAK
Related Pathways
Cytoskeletal Signaling
Bioactivity
KT D606 is a PAK kinase family inhibitor with an IC50 of 4 ?M. It selectively inhibits the proliferation of cancer cells transformed by oncogenic RAS mutants, making it useful for studying RAS/PAK1-induced cancers.
Smiles
C[C@]12N3C=4C5=C(C6=C(C4C=7C3=CC=CC7)C(CCCCCCCC8C=9C%10=C%11C%12=C(C9C(=O)N8)C=%13C(N%12[C@@]%14(O[C@](C)(N%11C=%15C%10=CC=CC%15)[C@](C(O)=O)(O)C%14)[H])=CC=CC%13)NC6=O)C=%16C(N5[C@](O1)(C[C@@]2(C(O)=O)O)[H])=CC=CC%16
Molecular Formula
C59H50N6O10
Molecular Weight
1003.06
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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