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GPX4-IN-14

Product Specifications

Target

Ferroptosis, Reactive Oxygen Species, Glutathione Peroxidase

Related Pathways

NF-κB, Apoptosis, Immunology/Inflammation, Metabolism

Bioactivity

GPX4-IN-14 (compound 2c) acts as a GPX4 inhibitor, exhibiting both free radical scavenging activity (with a maximum scavenging rate of 72.52%) and anti-tumor proliferation activity in vitro. This compound targets GPX4 protein, elevating lipid peroxide and intracellular Reactive Oxygen Species (ROS) levels, which induces ferroptosis and contributes to its anti-tumor proliferation effects.

Molecular Formula

C26H39NO8Se

Molecular Weight

572.55

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Available Sizes

Frequently Asked Questions

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