PMED-1
Product Specifications
CAS Number
491828-75-2
Target
Wnt/beta-catenin
Related Pathways
Stem Cells|||Cytoskeletal Signaling
Bioactivity
PMED-1, a ?-catenin inhibitor, effectively suppresses ?-catenin activity in hepatoblastoma cells and various HCC (Hepatocellular Carcinoma) cells with IC50 values ranging from 4.87 to 32 ?M. It impedes cell proliferation by disrupting the interaction between ?-catenin and CREB-binding protein, thus affecting Wnt signaling pathways. PMED-1 is utilized in cancer research studies.
Smiles
O=C(NC=1C=NN(C1)CC2=CC=C(F)C=C2)C3CC3C=4C=CC=CC4
Molecular Formula
C20H18FN3O
Molecular Weight
335.38
Shipping Conditions
Cool pack
Storage Temperature
-20°C
Available Sizes
Curated Selection
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