KRAS inhibitor-31
Product Specifications
CAS Number
2920695-77-6
Target
Ras
Related Pathways
MAPK, GPCR/G Protein
Bioactivity
KRAS inhibitor-31 (compound 33), a potent agent targeting KRAS, exhibits K D (SPR) values of 0.019 nM for KRas G12D, 0.019 nM for KRas G12C, and 0.096 nM for KRas G12V, illustrating its efficacy across these variants.
Smiles
FC=1C=2C3=C(N4[C@](COC3=NC1C=5C6=C(C=C(O)C5)C=CC(F)=C6C#C)(COCCC4)[H])N=C(OC[C@@]78N(C[C@H](F)C7)CCC8)N2
Molecular Formula
C33H30F3N5O4
Molecular Weight
617.62
Shipping Conditions
Ice Packs
Storage Temperature
-20°C
Available Sizes
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